Publications

In this section you will find a list of LJH publications and a link to the article itself - a number of these papers are open access.

Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells

  • Nigam S, Burke BP, Davies LH, Domarkas J, Wallis JF, Waddell PG, Waby JS, Benoit DM, Seymour AM, Cawthorne C, Higham LJ, Archibald SJ
  • Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells
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Evidence of Slow Magnetic Relaxation in Co(AcO)2(py)2(H2O)2

  • Walsh JPS, Bowling G, Ariciu A-M, Jailani NFM, Chilton NF, Waddell PG, Collison D, Tuna F, Higham LJ
  • Evidence of Slow Magnetic Relaxation in Co(AcO)2(py)2(H2O)2
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The design of second generation MOP-phosphonites: efficient chiral hydrosilylation of functionalised styrenes

  • Fleming JT, Ficks A, Waddell PG, Harrington RW, Higham LJ
  • The design of second generation MOP-phosphonites: efficient chiral hydrosilylation of functionalised styrenes
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Air-stable fluorescent primary phosphine complexes of molybdenum and tungsten

  • Davies LH, Wallis JF, Harrington RW, Waddell PG, Higham LJ
  • Air-stable fluorescent primary phosphine complexes of molybdenum and tungsten
  • Visit

Zirconium-catalyzed intermolecular hydrophosphination using a chiral, air-stable primary phosphine

  • Bange CA, Ghebreab MB, Ficks A, Mucha NT, Higham LJ, Waterman R
  • Zirconium-catalyzed intermolecular hydrophosphination using a chiral, air-stable primary phosphine
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Setting P-Donor Ligands into Context: An Application of the Ligand Knowledge Base (LKB) Approach

  • Fey N, Papadouli S, Pringle PG, Ficks A, Fleming JT, Higham LJ, Wallis JF, Carmichael D, Mézailles N, Müller C
  • Setting P-Donor Ligands into Context: An Application of the Ligand Knowledge Base (LKB) Approach
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Primary Phosphine Chemistry

  • Fleming JT, Higham LJ
  • Primary Phosphine Chemistry
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BR2BodPR2: highly fluorescent alternatives to PPh3 and PhPCy2

  • Davies LH, Harrington RW, Clegg W, Higham LJ
  • BR2BodPR2: highly fluorescent alternatives to PPh3 and PhPCy2
  • Visit

Re and 99mTc complexes of BodP3 – multi-modality imaging probes

  • Davies LH, Kasten BB, Benny PD, Arrowsmith RL, Ge H, Pascu SI, Botchway SW, Clegg W, Harrington RW, Higham LJ
  • Re and 99mTc complexes of BodP3 – multi-modality imaging probes
  • Visit

Air-Stable, Fluorescent Primary Phosphines

  • Davies LH, Stewart B, Higham LJ
  • Air-Stable, Fluorescent Primary Phosphines
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Air-Stable Chiral Primary Phosphines: A Gateway to MOP Ligands with Previously Inaccessible Stereoelectronic Profiles

  • Ficks A, Clegg W, Harrington RW, Higham LJ
  • Air-Stable Chiral Primary Phosphines: A Gateway to MOP Ligands with Previously Inaccessible Stereoelectronic Profiles
  • Visit

Efficient Multigram Syntheses of Air-Stable, Fluorescent Primary Phosphines via Palladium-Catalyzed Phosphonylation of Aryl Bromides

  • Davies LH, Wallis JF, Probert MR, Higham LJ
  • Efficient Multigram Syntheses of Air-Stable, Fluorescent Primary Phosphines via Palladium-Catalyzed Phosphonylation of Aryl Bromides
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Chiral MOP-phosphonite ligands: synthesis, characterisation and interconversion of η1,η6-(σ-P, π-arene) chelated rhodium(I) complexes

  • Ficks A, Harrington RW, Higham LJ
  • Chiral MOP-phosphonite ligands: synthesis, characterisation and interconversion of η1,η6-(σ-P, π-arene) chelated rhodium(I) complexes
  • Visit

Efficient Multigram Syntheses of Air-Stable, Chiral Primary Phosphine Ligand Precursors via Palladium-Catalyzed Phosphonylation of Aryltriflates

  • Ficks A, Sibbald C, Ojo S, Harrington RW, Clegg W, Higham LJ
  • Efficient Multigram Syntheses of Air-Stable, Chiral Primary Phosphine Ligand Precursors via Palladium-Catalyzed Phosphonylation of Aryltriflates
  • Visit

Air-Stable Chiral Primary Phosphines Part (ii) Predicting the Air-Stability of Phosphines

  • Stewart B, Harriman A, Higham LJ
  • Air-Stable Chiral Primary Phosphines Part (ii) Predicting the Air-Stability of Phosphines
  • Visit

Naphthoxaphospholes as examples of fluorescent phospha-acenes

  • Laughlin FL, Rheingold AL, Deligonul N, Laughlin BJ, Smith RC, Higham LJ, Protasiewicz JD
  • Naphthoxaphospholes as examples of fluorescent phospha-acenes
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Air-Stable, Highly Fluorescent Primary Phosphanes

  • Davies LH, Stewart B, Harrington RW, Clegg W, Higham LJ
  • Air-Stable, Highly Fluorescent Primary Phosphanes
  • Visit

MOP-phosphonites: A novel ligand class for asymmetric catalysis

  • Ficks A, Hiney RM, Harrington RW, Gilheany DG, Higham LJ
  • MOP-phosphonites: A novel ligand class for asymmetric catalysis
  • Visit

Anomalous Z-isomer content in Wittig reaction products from keto-stabilised ylides with ortho-heteroatom substituted benzaldehydes

  • Byrne PA, Higham LJ, McGovern P, Gilheany DG
  • Anomalous Z-isomer content in Wittig reaction products from keto-stabilised ylides with ortho-heteroatom substituted benzaldehydes
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Predicting the Air Stability of Phosphines

  • Stewart B, Harriman A, Higham LJ
  • Predicting the Air Stability of Phosphines
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Taming Functionality: Easy-To-Handle Chiral Phosphiranes

  • Ficks A, Martinez-Botella I, Stewart B, Harrington RW, Clegg W, Higham LJ
  • Taming Functionality: Easy-To-Handle Chiral Phosphiranes
  • Visit

The Synthesis of P-Stereogenic MOP Analogues and their use in Rhodium Catalysed Asymmetric Addition

  • Clarke EF, Rafter E, Müller-Bunz H, Higham LJ, Gilheany DG
  • The Synthesis of P-Stereogenic MOP Analogues and their use in Rhodium Catalysed Asymmetric Addition
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The Primary Phosphine Renaissance

  • Higham LJ
  • The Primary Phosphine Renaissance
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Air-stable Chiral Primary Phosphines: Part (i) Synthesis, Stability and Reactivity

  • Hiney RM, Ficks A, Müller-Bunz H, Gilheany DG, Higham LJ
  • Air-stable Chiral Primary Phosphines: Part (i) Synthesis, Stability and Reactivity
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A re-evaluation of the electrophilic substitution reactions of the Ramirez ylide

  • Higham LJ, Muldoon J, Kelly PG, Corr DM, Muller-Bunz H, Gilheany DG
  • A re-evaluation of the electrophilic substitution reactions of the Ramirez ylide
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Taming a functional group: Creating air-stable, chiral primary phosphanes

  • Hiney RM, Higham LJ, Muller-Bunz H, Gilheany DG
  • Taming a functional group: Creating air-stable, chiral primary phosphanes
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P-chirogenic phosphines. MOP/diPAMP hybrids, their oxide crystal structures, reduction studies and alternative syntheses

  • Higham LJ, Clarke EF, Muller-Bunz H, Gilheany DG
  • P-chirogenic phosphines. MOP/diPAMP hybrids, their oxide crystal structures, reduction studies and alternative syntheses
  • Visit

A novel azulene synthesis from the Ramirez ylide involving two different modes of its reaction with activated alkynes

  • Higham LJ, Kelly PG, Corr DM, Müller-Bunz H, Walker BJ, Gilheany DG.
  • A novel azulene synthesis from the Ramirez ylide involving two different modes of its reaction with activated alkynes
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{(E)- and {(Z)-2-[α,β-bis(methoxy-carbonyl)vinyl]cyclopentadien-1-ylidene}triphenylphosphorane

  • Higham LJ, Kelly PG, Muller-Bunz H, Gilheany DG.
  • {(E)- and {(Z)-2-[α,β-bis(methoxy-carbonyl)vinyl]cyclopentadien-1-ylidene}triphenylphosphorane
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2,2′-Bis((di-tert-butylphosphino)methyl)-1,1′-biphenyl (ditbi): a bulky analogue of bisbi. The crystal structure of [Rh2Cl2(1,5-cod)2(μ-ditbi)]

  • Higham LJ, Heslop K, Pringle PG, Orpen AG
  • 2,2′-Bis((di-tert-butylphosphino)methyl)-1,1′-biphenyl (ditbi): a bulky analogue of bisbi. The crystal structure of [Rh2Cl2(1,5-cod)2(μ-ditbi)]
  • Visit

Chelates formed by a constrained bis(diphenylphosphino)xylene; the crystal structures of [FeCl2(anphos)] and [RhCl(CO)(anphos-monoxide)]

  • Higham LJ, Middleton AJ, Heslop K, Pringle PG, Barber A, Orpen AG
  • Chelates formed by a constrained bis(diphenylphosphino)xylene; the crystal structures of [FeCl2(anphos)] and [RhCl(CO)(anphos-monoxide)]
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Water-soluble hydroxyalkylated phosphines: examples of their differing behaviour toward ruthenium and rhodium

  • Higham LJ, Whittlesey MK, Wood PT
  • Water-soluble hydroxyalkylated phosphines: examples of their differing behaviour toward ruthenium and rhodium
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Formation and X-ray structure of a novel water-soluble tertiary-secondary phosphine complex of ruthenium(II): [Ru{P(CH2OH)3}2{P(CH2OH)2H}2Cl2]

  • Higham L, Powell AK, Whittlesey MK, Wocadlo S, Wood PT
  • Formation and X-ray structure of a novel water-soluble tertiary-secondary phosphine complex of ruthenium(II): [Ru{P(CH2OH)3}2{P(CH2OH)2H}2Cl2]
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Synthesis and structure of bis[2,2′-methylenebis(2,4-di-t-butylphenoxo)]niobium chloride

  • Higham L, Thornton-Pett M, Bochmann M
  • Synthesis and structure of bis[2,2′-methylenebis(2,4-di-t-butylphenoxo)]niobium chloride
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