Latest updates

Copper catalysts give 1-phosphapyracenes from LJH primary phosphines: a new US collaboration

– Posted on 16.06.2020

Read all about our collaboration with the Glueck research group in Organometallics on the synthesis of chiral 1-phosphapyracenes from our air-stable chiral MOP primary phosphines – carried out at Newcastle University, UK and Dartmouth College, USA:

Copper–Phosphido Intermediates in Cu(IPr)-Catalyzed Synthesis of 1-Phosphapyracenes via Tandem Alkylation/Arylation of Primary Phosphines

 

 

New collaboration with the Redshaw group on rhenium and technetium radiopharmaceuticals!

– Posted on 16.06.2020

We have been working with our collaborators in the Redshaw and Archibald groups to synthesise rhenium complexes with the water-soluble PTA ligand. These compounds are of relevance to nuclear medicine and you can read about their preparation and cell studies at the link below:

Water-Soluble Rhenium Phosphine Complexes Incorporating the Ph2C(X) Motif (X = O, NH): Structural and Cytotoxicity Studies

 

Jenny wins 1st Prize at EngD 2016

– Posted on 12.07.2016

Well done to Jenny who won first prize for her presentation on ‘The Synthesis of Fluorescent Phosphorus Ligands and their Applications in Catalysis and Medical Imaging’ at the annual EngD conference at The Baltic this month. Jenny was supported by Bob Redfern and Roy Valentine of High Force Research Ltd who have co-sponsored her throughout her postgraduate studies.

Jenny Bob and Roy EngD 2016

You can read more about Jenny’s work on mitochondrial imaging agents here.

Congratulations to Sophie, Steve and Vincent

– Posted on 12.07.2016

Congratulations go to the 2016 LJH MChem students who all worked very hard and carried out successful research projects. Steven worked on the synthesis of interesting polynuclear lanthanide complexes, whilst both Vincent and Sophie worked on preparing novel Bodipy phosphine dyes for biological cell imaging. Enjoy your forthcoming graduation and best wishes for the future.

Welcome to Charlotte who starts her PhD with the team.

– Posted on 02.10.2015

The LJH group would like to welcome our newest recruit, Charlotte Hepples. Charlotte graduated this summer from the School of Chemistry here at Newcastle, after spending a very successful year abroad at the University of Waterloo, as part of our Study Abroad undergraduate programme. She will research novel highly fluorescent phosphorus(III) compounds for use as imaging agents.